Endocrine Abstracts

Thyroid disorders and polycystic ovary syndrome (PCOS) are two of the most common endocrine disorders in general population. Autoimmune thyroid diseases are common autoimmune disorders that affect about 5% to 20% of women in childbearing age. In this study, we evaluate the comorbidity rate of euthyroid Hashimoto’s Thyroiditis (HT) in PCOS patients and possible influence of thyroid autoantibodies on clinical and laboratory findings of PCOS. This study includes 285 PCOS pat...

Aim: Hashimoto’s thyroiditis (HT) is an autoimmune disease in which a breakdown of immune tolerance is caused by interplay of a variety of immunologic, genetic, and environmental factors. Mean platelet volume (MPV) is the measure of platelet size. MPV possibly is a simple way to estimate platelet activity. Activated platelets play an important role in the pathogenesis of vascular disease especially coronary heart diseases. Larger platelets are metabolically and enzymatica...

Aim: 402 patients who were admitted and FNA was done in the Endocrinology Clinic at EBEAH were enrolled in this study. 340 (85%) of them were females and 62 (15%) of them were males. The age range was between 16 and 82. There weren’t any statistical differences in age between both sexes. Thyroid cancer is reported to constitute <2% of cancers in humans. At the same time, it is the most lethal endocrine malignancy. In the literature it is stated that 3% of all cancers ...

The pathologist cannot easily decide some thyroid fine-needle aspiration biopsy (FNA) into the benign, suspicious, or malignity and this condition are reported as ‘atypia of undetermined significance’ (AUS) or ‘follicular lesion of undetermined significance’ in the Bethesda system. Diagnosis of AUS of a thyroid nodule is leaved an endocrinologist as well as the patients in a difficult situation. However, the risk of malignancy at AUS is ~5–15%. Our aim...

Introduction and aim: Bethesda system for thyroid cytopathology has been widely used recently. Approximately 3–7% of thyroid fine-needle aspiration (FNA) biopsy is considered as malign. Suspicious or malign nodules should likely to be resected. Aim of this study is to confirm the diagnosis of malign or suspicious for malignity according to Bethesda classification in patients with nodular goitre after thyroidectomy.Materials and methods: Results of F...

Introduction and aim: Interpretation of follicular neoplasia classification according to Bethesda system in thyroid fine needle aspiration biopsy is very different among pathologist. A number of definition including ‘follicular lesion’, ‘follicular proliferation’, ‘follicular lesion of undetermined significance’, and ‘follicular neoplasia’ were used in terminology. A clearly discrimination between nodular goitre, follicular adenoma, and ...

Introduction and aim: The most endocrinologists in routine practice are used to Bethesda classification for evaluation of thyroid nodule in fine needle aspiration biopsy (FNA). It is accepted that FNA biopsy is an accurate diagnostic and gold standard test. However, false-positive diagnosis may sometimes occur as a patient with a ‘malign’ lesion is found incorrectly rather than an actually benign lesion on histological examination. Hashimoto’s thyroiditis probab...

Adequacy of thyroid fine-needle aspiration (FNA) is generally defined by the thyroid follicle cells, amount, and quality of colloid. Samples priorly should be evaluated for adequacy. A set of qualifying criteria are specified in Bethesda system to remove subjectivity from the adequacy assessment. Each sample prepared from a thyroid FNA should be monitored at least six follicles cell groups containing at least ten cells. In addition to these criteria of assessing the adequacy, ...

Fine-needle aspiration biopsies (FNAB), adequate for examination, reported as benign re-evaluated with histopathological samples. 61 patients, 52 females and nine males re-evaluated. 41 of them reported as benign. 20 of the patients, seven females and three males reported as papillary carcinoma. Six of the papillary carcinomas were single focus, two muiticentric, and 12 papillary microcarcinoma. Six of the eight patients malignant lobe was different from the lobe that FNA was ...

Introduction and aim: Fine-needle aspiration (FNA) biopsy has become widely accepted as a reliable method for diagnosis of malign thyroid nodule. In our study we aimed to review results of thyroid FNA biopsy to be performed by same endocrinologist and compared to their histopathological results after thyroidectomy.Materials and methods: This retrospective study was done at the department of pathology for a period of 2 years from 2012 to 2014. The 401 pat...